dynamic lists and segmentation in wordfly

I'm having trouble with triggered wordfly emails I'm trying to send and I think my issue is the way I have set up my criteria in list builder.

I have 10 lists.  All dynamic.  Each list uses the previous list as a suppression and therefore need to be generated in order to be accurate.  For example: 

List 1 criteria - several AND statements.

List 2 criteria-  AND NOT EXIST List 1.

List 3 criteria- AND NOT EXIST List 1 and 2.

etc...etc....etc... 

I think I'm getting the sense that Tessitura uses a lot of energy to go through all the dynamic lists to suppress.  Now I'm at the last 2 lists and they have practically taken 5 minutes to generate. 

Normally, I would just make an extraction, but this needs to be a triggered email in wordfly, so we can't use extractions as a triggered email list.  Only dynamic lists... :(

Any ideas?

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